Joined later by Alan Scott Douglas and Patricia Tamowski cofounders of Health Advocates Worldwide, an organization that educates the public about health and addresses causes of diseasethese four presenters use case studies and fact-based presentations to speak about the different modalities used to cure the symptoms of dementia. Module 2 - David Perlmutter Part 1 This module is part 1 of a 2 part presentation from David Perlmutter, MD, who shares his hopes for a paradigm shift in the way the medical establishment looks at a whole host of degenerative diseases. Learn how to take control of your health with daily exercise and proper nutrition, and how detoxing can prevent and reverse the symptoms of dementia.
This Part 1 write-up was inspired by a recent small, non-randomized clinical trial done by Dr.
Not all of these patients had AD, but all had cognitive decline. We explore those 25 interventions here, focusing on the first They do not depend on drugs. We review major theories related to AD there including the Hardy Hypothesis related to amloid beta, the GSK3 theory and more detail on the neuroinflammation theory which we introduce in this Part 1 blog entry.
And we will describe some very recent research that appears to establish that a basic cause of AD is the proliferation in aging of vestigal DNA segments in our genomes known as LINEs which are long interspersed nuclear elements and SINEs which are short interspersed nuclear elements with encode over and over again for the production of APP and for the failure of its clearance.
This could well finally explain the role of beta amyloid in AD. We have published a number of earlier blog entries relating to AD and dementias.
A portrayal of the breakdown follows. Since AD and VaD are clearly the leading causes of dementia world-wide, we will focus mostly on these two types of dementia. Bythese numbers will be 13 million US and million world-wide Ferri, Many experts now regard dementia from neurodegenerative diseases as the 3rd leading cause of death after cardiovascular disease and cancer.
Despite millions of dollars being spent annually on research, the exact causes of these dementias are still unknown, but the number of clues to the causes is growing and we will explore some of the main ones in our Part 2 blog entry.
We return to neuroinflammation several times as a central theme here and in the Part 2 blog entries. In these familial cases, there is most often a genetic mutation that is causal in nature early onset disease or a single nucleotide polymorphism SNP that is not causal in nature, but predisposes the patient to the disease.
Environmental risk factors for neurodegenerative diseases are discussed in the publication Neurodegenerative Diseases: Despite millions of dollars being spent annually on research, the exact cause of these dementias are still unknown, but the number of clues to the cause is growing.
Failure of Monotherapeutic Approaches to Neurodegeneration — It is time to consider multiple component therapies The development of drugs to treat neurodegeneration has probably been the biggest failure of the pharmaceutical industry.
Although there are three FDA-approved drugs for AD, none of them produce anything other than a marginal, unsustained effect on symptoms. Hundreds of clinical trials for AD have failed over the past two decades, most recently being the large Phase III trials of monoclonal antibodies that target amyloid-beta.
As of today, no drugs have been approved for Frontotemporal dementia, Vascular dementia, and Lewy body dementia. Only one drug has been approved for Amyotrophic lateral sclerosis ALS.
All of the clinical trials done for these diseases have largely been with monotherapeutic drug approaches. We know from the field of cardiovascular disease, cancer, and HIV that single drug therapy for these diseases largely fail.Here is where the potential links to Alzheimer's disease can be found, says Brian Giunta, MD, PhD, a psychiatrist and neuroscientist at the University of Southern Florida.
Advertisement - Continue. 1. About this report. Alzheimer's Disease Facts and Figures is a statistical resource for U.S. data related to Alzheimer's disease, the most common cause of dementia. Background and context for interpretation of the data are contained in the overview.
Myth: Cholesterol Causes Alzheimer's Disease Part I: Debunking the Myth. by Chris Masterjohn. Published August 1, Cholesterol is widely blamed for causing Alzheimer's disease.
Results from a new study may lead to approval of what could be the first drug that ameliorates potentially deadly reactions in children with severe peanut allergies.
Aug 14, · The accumulation of a specific protein in the aging brain may be the cause of numerous devastating neurodegenerative diseases – . Chemical and molecular biology of Alzheimer's Disease.